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The standard garb of laboratory workers also began to shift to white during the turn of the 20th century, when the relationship between medicine and laboratory science became more entwined. Lab scientists likely adopted surgical fashion as a result. In 1898, Sir William Osler, a Canadian physician already known for writing some of the first clinical laboratory literature, introduced ward laboratories at Johns Hopkins Hospital. Gradually, surgical practice relied on laboratories for tools, microscopes, chemical assays, pathology reports, and bacterial cultures to diagnose patients.